Wednesday, October 14, 2009

Einstein's Telescope: Searching for Dark Matter and the Future of the Universe


Einstein_ring_2“Such stunning cosmic coincidences reveal so much about nature.”

~ Leonidas Moustakas, Jet Propulsion Laboratory

The Hubble Space Telescope has revealed a never-before-seen optical alignment in space: a pair of glowing rings, one nestled inside the other like a bull's-eye pattern. The double-ring pattern is caused by the complex bending of light from two distant galaxies strung directly behind a foreground massive galaxy, like three beads on a string. The foreground galaxy is 3 billion light-years away, the inner ring and outer ring are comprised of multiple images of two galaxies at a distance of 6 and approximately 11 billion light-years.

The discovery was made by an international team of astronomers led by Raphael Gavazzi and Tommaso Treu of the University of Californi, Santa Barbara. Treu says the odds of seeing such a special alignment are so small that they “hit the jackpot” with this discovery. “When I first saw it I said ‘wow, this is insane!’ I could not believe it!”

But this sight is more than just an incredible novelty. It’s also a very rare phenomenon that can offer insights into dark matter, dark energy, the nature of distant galaxies, and the curvature of the Universe itself. The discovery is part of the ongoing Sloan Lens Advanced Camera for Surveys (SLACS) program.

The phenomenon, called gravitational lensing, occurs when a massive galaxy in the foreground bends the light rays from a distant galaxy behind it, in much the same way as a magnifying glass would. When both galaxies are perfectly lined up, the light forms a circle, called an “Einstein ring”, around the foreground galaxy. If another more distant galaxy lies precisely on the same sightline, a second, larger ring will appear.

“Such stunning cosmic coincidences reveal so much about nature. Dark matter is not hidden to lensing,” added Leonidas Moustakas of the Jet Propulsion Laboratory in Pasaden, California, USA. “The elegance of this lens is trumped only by the secrets of nature that it reveals.”

The dark matter distribution in the foreground galaxies that is warping space to create the Einstein's telescope, the gravitational lens, can be accurately mapped. In addition, the geometry of the two Einstein rings allowed the team to measure the mass of the middle galaxy precisely to be a value of 1 billion solar masses. The team reports that this is the first measurement of the mass of a dwarf galaxy at cosmological distance.

A sample of several dozen double rings such as this one would offer a purely independent measure of the curvature of space by gravity. This would help in determining what the majority of the Universe is made of, and the properties of dark energy.

Original observations made in 1970 revealed that gravitational motions of gas clouds in the Andromeda galaxy were occurring at speeds far greater than the entire observed mass of that galaxy could account for. Similar problems detected in the 1930's involving motions of entire galaxies had long been disregarded. Later observations confirmed that so-called "ordinary matter" is insufficient to account for observed gravitational effects in the cosmos. Thus the universe must contain huge amounts of "dark matter," that we cannot observe and the composition of which we do not know.

In 1998 reports of observations of distant supernovae revealed that the expansion of the universe was not slowing, as would be expected from long-term effects of gravity, but was instead accelerating. Something was overcoming the gravitational power of all of the matter in the universe. The acceleration, moreover, has not been present from the Big Bang on. For billions of years the speed of expansion slowed. Then, about 5 billion years ago, acceleration began. Obviously energy--a lot of it--- was required to explain these phenomena. This is "dark energy." We cannot detect it and currently know almost nothing about it.

Today scientists believe that 5% of the universe consists of "ordinary" [observable] matter, 23% of "dark" matter and 72% of "dark energy."

Einstein's Telescope: Searching for Dark Matter and the Future of the Universe


Einstein_ring_2“Such stunning cosmic coincidences reveal so much about nature.”

~ Leonidas Moustakas, Jet Propulsion Laboratory

The Hubble Space Telescope has revealed a never-before-seen optical alignment in space: a pair of glowing rings, one nestled inside the other like a bull's-eye pattern. The double-ring pattern is caused by the complex bending of light from two distant galaxies strung directly behind a foreground massive galaxy, like three beads on a string. The foreground galaxy is 3 billion light-years away, the inner ring and outer ring are comprised of multiple images of two galaxies at a distance of 6 and approximately 11 billion light-years.

The discovery was made by an international team of astronomers led by Raphael Gavazzi and Tommaso Treu of the University of Californi, Santa Barbara. Treu says the odds of seeing such a special alignment are so small that they “hit the jackpot” with this discovery. “When I first saw it I said ‘wow, this is insane!’ I could not believe it!”

But this sight is more than just an incredible novelty. It’s also a very rare phenomenon that can offer insights into dark matter, dark energy, the nature of distant galaxies, and the curvature of the Universe itself. The discovery is part of the ongoing Sloan Lens Advanced Camera for Surveys (SLACS) program.

The phenomenon, called gravitational lensing, occurs when a massive galaxy in the foreground bends the light rays from a distant galaxy behind it, in much the same way as a magnifying glass would. When both galaxies are perfectly lined up, the light forms a circle, called an “Einstein ring”, around the foreground galaxy. If another more distant galaxy lies precisely on the same sightline, a second, larger ring will appear.

“Such stunning cosmic coincidences reveal so much about nature. Dark matter is not hidden to lensing,” added Leonidas Moustakas of the Jet Propulsion Laboratory in Pasaden, California, USA. “The elegance of this lens is trumped only by the secrets of nature that it reveals.”

The dark matter distribution in the foreground galaxies that is warping space to create the Einstein's telescope, the gravitational lens, can be accurately mapped. In addition, the geometry of the two Einstein rings allowed the team to measure the mass of the middle galaxy precisely to be a value of 1 billion solar masses. The team reports that this is the first measurement of the mass of a dwarf galaxy at cosmological distance.

A sample of several dozen double rings such as this one would offer a purely independent measure of the curvature of space by gravity. This would help in determining what the majority of the Universe is made of, and the properties of dark energy.

Original observations made in 1970 revealed that gravitational motions of gas clouds in the Andromeda galaxy were occurring at speeds far greater than the entire observed mass of that galaxy could account for. Similar problems detected in the 1930's involving motions of entire galaxies had long been disregarded. Later observations confirmed that so-called "ordinary matter" is insufficient to account for observed gravitational effects in the cosmos. Thus the universe must contain huge amounts of "dark matter," that we cannot observe and the composition of which we do not know.

In 1998 reports of observations of distant supernovae revealed that the expansion of the universe was not slowing, as would be expected from long-term effects of gravity, but was instead accelerating. Something was overcoming the gravitational power of all of the matter in the universe. The acceleration, moreover, has not been present from the Big Bang on. For billions of years the speed of expansion slowed. Then, about 5 billion years ago, acceleration began. Obviously energy--a lot of it--- was required to explain these phenomena. This is "dark energy." We cannot detect it and currently know almost nothing about it.

Today scientists believe that 5% of the universe consists of "ordinary" [observable] matter, 23% of "dark" matter and 72% of "dark energy."

Tuesday, October 13, 2009

Sex In The Caribbean: Environmental Change Drives Evolutionary Change, Eventually

Hungry, sexual organisms replaced well-fed, clonal organisms in the Caribbean Sea as the Isthmus of Panama arose, separating the Caribbean from the Pacific, report researchers from the Smithsonian Tropical Research Institute and Scripps Institution of Oceanography. The fossil record shows that if a species could shift from clonal to sexual reproduction it survived. Otherwise it was destined for extinction, millions of years later.


Image:Tiny bryozoans in sediments dredged
up from the bottom of the Caribbean Sea
reveal that environmental change drove evolution.

Closure of the Isthmus of Panama involved a protracted sequence of volcanic and tectonic events. During the final phase, between about 4.5 and 3.5 million years ago, the Caribbean underwent a major change from a pea soup-like environment, fed by nutrient-rich waters surging up along South America, into a crystal-clear, nutrient-poor environment.

"As the Caribbean Sea was cut off from the Pacific Ocean, many new species appeared in the fossil record, and all reproduced sexually," said Aaron O'Dea, who holds a Tupper Postdoctoral Fellowship at the Smithsonian Tropical Research Institute.

Well-preserved fossils show that cupuladriid bryozoans, colonial animals similar to corals that walk around on the sea floor, reproduced either by cloning or by sex. To clone a new colony requires immediately available energy, so when nutrients are scarce, it's better not to fragment. Nutrients to form eggs and sperm needed for sex can, on the other hand, accumulate slowly over time.

O'Dea, with Jeremy Jackson, emeritus staff scientist at the Smithsonian and director of the Center for Marine Biodiversity and Conservation at Scripps Institution of Oceanography, measured the relative amount of cloning and sex occurring in species over the last 10 million years in the Caribbean. "The two forms are unmistakable," explained O'Dea. "You can clearly see the first individual that founded a sexual colony, while a clonal colony preserves the fragment from the previous colony from which it cloned."

As predicted, clonal bryozoans rapidly disappeared from the record as the Caribbean was isolated. Species that survived did so by becoming increasingly robust to reduce the chances of fragmentation while those that failed to evolve went extinct. They are still found in the nutrient-rich eastern Pacific.

But not everyone agreed that the extinctions which occurred 1-2 million years later in the Caribbean were caused by the formation of the Isthmus—a pattern also seen in corals and molluscs. Now these authors have the evidence to be sure.

"It's important to distinguish between ecological extinction—when these organisms stopped being important players in the game—and actual extinction, when they disappeared from the geological record," said Jackson. "The idea that extinction may be delayed by millions of years after the cause is worrisome. Today an overwhelming number of species are being reduced in abundance. The forecast from the fossil record is that even if they survive now, the ultimate cause of their extinction may already have passed us by."

Saturday, October 10, 2009

35 Years of the World’s Best Microscope Photography

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This image of the male sex organ of a flowering plant took first place in Nikon’s annual Small World photomicrography competition this year.

Chosen for both its scientific and artistic qualities from among a record 2,000 entries, this image was captured by Estonian scientist Heiti Paves.

“As part of my work as a research scientist, I have been taking photographs through the microscope for almost 30 years to observe the processes in living cells,” Paves said Thursday in a press release.

Nikon honored 20 images this year including an anglerfish ovary, cotton fibers and fish scales.

Winning the popular vote online out of 137 finalists was the image below of a bundle of fluorescent actin protein filaments captured by Dennis Breitsprecher of the Institute of Biophysical Chemistry at Germany’s Hannover Medical School.

Images: Above: Arabidopsis thaliana (thale cress) anther (20x) Confocal / Heiti Paves, Tallinn University of Technology, courtesy of Nikon Small World.

Below: Fluorescent actin protein filaments. / Dennis Breitsprecher, Institute of Biophysical Chemistry at Germany’s Hannover Medical School. Courtesy of Nikon Small World.

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Previous winners:

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2008: Pleurosigma (marine diatoms) (200x), Darkfield and Polarized Light. / Michael Stringer, Westcliff-on-Sea, Essex, United Kingdom. Courtesy of Nikon Small World. The 2008 runners up.

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2007: Double transgenic mouse embryo, 18.5 days (17x), Brightfield, Darkfield, Fluorescence (GFP and RFP). / Gloria Kwon, Memorial Sloan-Kettering Insititute. Courtesy of Nikon Small World. The 2007 runners up.

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2006: Mouse colon (740x), 2-Photon. / Paul L. Appleton, University of Dundee, UK. Courtesy of Nikon Small World. The 2006 runners up.

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2005: Muscoid fly (house fly) (6.25x), Reflected light. / Charles B. Krebs, Charles Krebs Photography, Issaquah, Washington, USA. Courtesy of Nikon Small World. The 2005 runners up.

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2004: Quantum dot nanocrystals deposited on a silicon substrate (200x), Polarized reflected light. / Seth A. Coe-Sullivan, Massachusetts Institute of Technology. Courtesy of Nikon Small World. The 2004 runners up.

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2003: Filamentous actin and microtubules (structural proteins) in mouse fibroblasts (cells) (1000x), Fluorescence. / Torsten Wittmann, The Scripps Research Institute. Courtesy of Nikon Small World. The 2003 runners up.

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2002: Sagittal section of rat cerebellum (40x), Fluorescence and Confocal. / Thomas J. Deerinck, National Center for Microscopy and Imaging Research, University of California, San Diego. Courtesy of Nikon Small World. The 2002 runners up.

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2001: Fresh water rotifer feeding among debris (200x), Darkfield. / Harold TaylorKensworth, UK. Courtesy of Nikon Small World. The 2001 runners up.

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2000: Avicennia marina (mangrove) leaf (40x), Fluorescence and Differential Interference Contrast. / Daphne Zbaeren-Colbourn, Bern, Switzerland. Courtesy of Nikon Small World. The 2000 runners up.

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1999: Newt lung cell in mitosis (5 different structures) (240x), Fluorescence. / Alexey Khodjakov, Wadsworth Center, New York State Department of Health. Courtesy of Nikon Small World. The 1999 runners up.

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1998: Endothelial cells (100x), Fluorescence, Double Exposure. / Jakob Zbaeren, Inselspital, Bern, Switzerland. Courtesy of Nikon Small World. The 1998 runners up.

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1997: Mouse fibroblasts (160x), Fluorescence. / Barbara A. Danowski, Union College. Courtesy of Nikon Small World. The 1997 runners up.

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1996: Doxorubin in methanol and dimethylbenzenesulfonic acid (80x), Polarized Light. / Lars BechNaarden, The Netherlands. Courtesy of Nikon Small World. The 1996 runners up.

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1995: Larva of Pleuronectidae (20x), Rheinberg Illumination and Polarized Light. / Christian Gautier, JACANA Press Agency, France. Courtesy of Nikon Small World. The 1995 runners up.

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1994: Cross-section of very young beech (40x), Brightfield. / Jean Rüegger-Deschenaux, Mikroskopische Gesellschaft, Zurich, Switzerland. Courtesy of Nikon Small World. The 1994 runners up.

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1993: Fossil Fusulinids in limestone (8x), Polarized Light. / Ron Sturm, Construction Technology Laboratories, Inc., Illinois, USA. COurtesy of Nikon Small World. The 1993 runners up.

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1992: 10-year old preparation of barbital, fenacetine, valium and acetic acid (35x), Polarized Light. / Lars BechDeurne, The Netherlands. Courtesy of Nikon Small World. The 1992 runners up.

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1991: Polyurethane elastic fiber bundle (25x), Polarized Light. / Marc Van Hove, Centexbel, Belgium. Courtesy of Nikon Small World. The 1991 runners up.

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1990: Crystals evaporated from solution of magnesium sulfate and tartaric acid (50x), Polarized Light. / Richard H. Lee, Argonne National Laboratory. Courtesy of Nikon Small World. The 1990 runners up.

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1989: Multiple exposure of a knitting machine needle (10x), Brightfield. / Marc Van Hove, Centexbel, Belgium. Courtesy of Nikon Small World. The 1989 runners up.

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1988: Gold residue and gold-coated bubbles in glassy matrix (20x), Brightfield. / David Smith, Queensland, Australia. Courtesy of Nikon Small World. The 1988 runners up.

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1987: Crystals of influenza virus neuraminidase isolated from terns (14x), Brightfield with Colored Filters. / Julie Macklin and Dr. Graeme Laver, Australian National University. Courtesy of Nikon Small World. The 1987 runners up.

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1986: Live water mount of Hydra viridissima capturing Daphnia pulex (10x), Darkfield. / Steven F. Lowry, University of Ulster at Coleraine, North Ireland. Courtesy of Nikon Small World. The 1986 runners up.

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1985: Formalin-fixed whole mount of a spiral nematode, multiple exposure (160x), Darkfield. / Jon D. Eisenback, North Carolina State University. Courtesy of Nikon Small World. The 1985 runners up.

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1984: Inclusions of goethite and hematite in Brazilian agate (30x), Transmitted light with reflected fiber-optic illumination. / John I. Kolvula, Gemological Institute of America. Courtesy of Nikon Small World. The 1984 runners up.

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1983: Suctorian attached to stalk of red algae, encircled by ring of diatoms (125x), Darkfield. / Elieen Roux, Bob Hope International Heart Research Institute. Courtesy of Nikon Small World. The 1983 runners up.

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1982: Silverberry scaly hair whole mount (400x), Brightfield. / Jon D. Eisenback, North Carolina State University. Courtesy of Nikon Small World. The 1982 runners up.

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1981: Collapsed bubbles from an annealed experimental electronic sealing glass (55x), Reflected Light, Nomarski Differential Interference Contrast. / David Gnizak, Ferro Corp., Independence, Ohio. Courtesy of Nikon Small World. The 1981 runners up.

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1980: Larvacean within its feeding structure dyed with red organic carmine which the larvacean syphoned in while filter feeding (20x), Underwater camera with multiple extension tubes. / James M. King, Marine Science Institute, University of California, Santa Barbara. Courtesy of Nikon Small World. The 1980 runners up.

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1979: Stalked protozoan attached to a filamentous green algae with bacteria on its surface (160x), Nomarski Differential Interference Contrast. / Paul W. Johnson, University of Rhode Island. Courtesy of Nikon Small World. The 1979 runners up.

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1978: Gold, vaporized in a tungsten boat, in a vacuum evaporator (55x), Vertical Illumination - Normarski Differential Interference. / David Gnizak, Independence, Ohio. Courtesy of Nikon Small World. The 1978 runners up.

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1977: Crystals of rutile (titanium dioxide) and tridymite (a polymorph of quartz) in a cobalt-rich glass (350x), Combined oblique illumination and reflected light. / James W. Smith, Independence, Ohio. Courtesy of Nikon Small World. The 1977 runners up.

Have Humans Entered a New Stage of Evolution?


Discovery_chan_id1_04a Although It has taken homo sapiens several million years to evolve from the apes, the useful information in our DNA, has probably changed by only a few million bits. So the rate of biological evolution in humans, Stephen Hawking points out in his Life in the Universe lecture, is about a bit a year.

"By contrast," Hawking says, "there are about 50,000 new books published in the English language each year, containing of the order of a hundred billion bits of information. Of course, the great majority of this information is garbage, and no use to any form of life. But, even so, the rate at which useful information can be added is millions, if not billions, higher than with DNA."

This means Hawking says that we have entered a new phase of evolution. "At first, evolution proceeded by natural selection, from random mutations. This Darwinian phase, lasted about three and a half billion years, and produced us, beings who developed language, to exchange information."

But what distinguishes us from our cave man ancestors is the knowledge that we have accumulated over the last ten thousand years, and particularly, Hawking points out, over the last three hundred.

"I think it is legitimate to take a broader view, and include externally transmitted information, as well as DNA, in the evolution of the human race," Hawking said.

In the last ten thousand years the human species has been in what Hawking calls, "an external transmission phase," where the internal record of information, handed down to succeeding generations in DNA, has not changed significantly. "But the external record, in books, and other long lasting forms of storage," Hawking says, "has grown enormously. Some people would use the term, evolution, only for the internally transmitted genetic material, and would object to it being applied to information handed down externally. But I think that is too narrow a view. We are more than just our genes."

The time scale for evolution, in the external transmission period, has collapsed to about 50 years, or less.

Stephen-hawkingMeanwhile, Hawking observes, our human brains "with which we process this information have evolved only on the Darwinian time scale, of hundreds of thousands of years. This is beginning to cause problems. In the 18th century, there was said to be a man who had read every book written. But nowadays, if you read one book a day, it would take you about 15,000 years to read through the books in a national Library. By which time, many more books would have been written."

But we are now entering a new phase, of what Hawking calls "self designed evolution," in which we will be able to change and improve our DNA. "At first," he continues "these changes will be confined to the repair of genetic defects, like cystic fibrosis, and muscular dystrophy. These are controlled by single genes, and so are fairly easy to identify, and correct. Other qualities, such as intelligence, are probably controlled by a large number of genes. It will be much more difficult to find them, and work out the relations between them. Nevertheless, I am sure that during the next century, people will discover how to modify both intelligence, and instincts like aggression."

If the human race manages to redesign itself, to reduce or eliminate the risk of self-destruction, we will probably reach out to the stars and colonize other planets. But this will be done, Hawking believes, with intelligent machines based on mechanical and electronic components, rather than macromolecules, which could eventually replace DNA based life, just as DNA may have replaced an earlier form of life.

Friday, October 9, 2009

Scientists identify bacterium that helps in formation of gold

Australian scientists have found that the bacterium Cupriavidus metallidurans catalyses the biomineralisation of gold by transforming toxic gold compounds to their metallic form using active cellular mechanism.

According to Frank Reith, leader of the research and working at the University of Adelaide, “A number of years ago we discovered that the metal-resistant bacterium Cupriavidus metallidurans occurred on gold grains from two sites in Australia.

“The sites are 3500 km apart, in southern New South Wales and northern Queensland, so when we found the same organism on grains from both sites we thought we were onto something,” he said.

“It made us wonder why these organisms live in this particular environment. The results of this study point to their involvement in the active detoxification of Au complexes leading to formation of gold biominerals,” he added.

The experiments showed that C. metallidurans rapidly accumulates toxic gold complexes from a solution prepared in the lab.

This process promotes gold toxicity, which pushes the bacterium to induce oxidative stress and metal resistance clusters as well as an as yet uncharacterized Au-specific gene cluster in order to defend its cellular integrity.

This leads to active biochemically-mediated reduction of gold complexes to nano-particulate, metallic gold, which may contribute to the growth of gold nuggets.

By determining what elements there are, scientists can see where the gold is located in relation to the cells.

For this study, scientists combined synchrotron techniques at the European Synchrotron Radiation Facility (ESRF) and the Advanced Photon Source (APS) and molecular microbial techniques to understand the biomineralisation in bacteria.

It is the first time that these techniques have been used in the same study, so Frank Reith brought together a multinational team of experts in both areas for the success of the experiment.

This is the first direct evidence that bacteria are actively involved in the cycling of rare and precious metals, such as gold.

These results open the doors to the production of biosensors.

“The discovery of an Au-specific operon means that we can now start to develop gold-specific biosensors, which will help mineral explorers to find new gold deposits,” said Reith.

Scientists identify bacterium that helps in formation of gold

Australian scientists have found that the bacterium Cupriavidus metallidurans catalyses the biomineralisation of gold by transforming toxic gold compounds to their metallic form using active cellular mechanism.

According to Frank Reith, leader of the research and working at the University of Adelaide, “A number of years ago we discovered that the metal-resistant bacterium Cupriavidus metallidurans occurred on gold grains from two sites in Australia.

“The sites are 3500 km apart, in southern New South Wales and northern Queensland, so when we found the same organism on grains from both sites we thought we were onto something,” he said.

“It made us wonder why these organisms live in this particular environment. The results of this study point to their involvement in the active detoxification of Au complexes leading to formation of gold biominerals,” he added.

The experiments showed that C. metallidurans rapidly accumulates toxic gold complexes from a solution prepared in the lab.

This process promotes gold toxicity, which pushes the bacterium to induce oxidative stress and metal resistance clusters as well as an as yet uncharacterized Au-specific gene cluster in order to defend its cellular integrity.

This leads to active biochemically-mediated reduction of gold complexes to nano-particulate, metallic gold, which may contribute to the growth of gold nuggets.

By determining what elements there are, scientists can see where the gold is located in relation to the cells.

For this study, scientists combined synchrotron techniques at the European Synchrotron Radiation Facility (ESRF) and the Advanced Photon Source (APS) and molecular microbial techniques to understand the biomineralisation in bacteria.

It is the first time that these techniques have been used in the same study, so Frank Reith brought together a multinational team of experts in both areas for the success of the experiment.

This is the first direct evidence that bacteria are actively involved in the cycling of rare and precious metals, such as gold.

These results open the doors to the production of biosensors.

“The discovery of an Au-specific operon means that we can now start to develop gold-specific biosensors, which will help mineral explorers to find new gold deposits,” said Reith.

What's Left in the Cosmic Fuel Tank? Hundred Thousand Million Billion Trillion Quadrillion Quintillion Sextillion Septillion J/K

500x_DrDanger_01 Everyone knows that everything ends, with the possible exception of Madonna's career, but only scientists can take omniversal extinction and put it into equation. Some scientists have summed up everything that ever was, is, or will be, and put a number on how much can be done before "Heat Death" stops being an awesome name for a band and starts an eternal reality.



The idea is based on entropy, an incredibly important term which - just for kicks - has at least three different definitions. You can simply understand entropy as a measure of irreversible changes: you can move a vase back and forth between coffee table and shelf forever, but you can't undo dropping it. Entropy measures this kind of change in which energy wasted, the number of possible configurations, or the simple number of un-undoable anythings increases. The Second Law of Thermodynamics states that this value is always increasing - and in combination with the fact there's a finite amount of energy, it indicates that everything will eventually run down and stop. Or we'll have to feed the entire universe through a singularity (as in the Big Crunch) and start all over again - either way, the old universe is screwed.

Now Dr Charles Lineweaver and PhD student Charles Egan of the Australian National University have calculated how much entropy there is to "use up" - and it's a mere 10^104 Joules per Kelvin. Sure, a hundred thousand million billion trillion quadrillion quintillion sextillion septillion J/K might sound like an awful lot of whatever-that-is, but it's the ultimate finite supply. Forget oil - once you're out of entropy the game is well and truly over.

Of course this all about as relevant as ADD-afflicted mayflies calculating the thermonuclear lifespan of the sun, but it's fascinating in implication. The philosophical effects of their being a hard physical limit on how much can actually be done in any one universe are mind-blowing, as well as somehow making Dancing With The Stars an even worse affront to existence than it already was.

Your life is limited, fuel is finite, and even the ability to act itself is now a non-renewable resource. So make yourself worthwhile!